|
KMID : 1037820170060020037
|
|
Journal of Pain and Autonomic Disorders
2017 Volume.6 No. 2 p.37 ~ p.40
|
|
|
Supine Hypertension Aggravated by Duloxetine in a Patient with Diabetic Autonomic Neuropathy
|
|
Sohn Sung-Yeon
Kim Jae-Guk
Choi Han-Na
Kim Do-Hyung
Jang Sang-Hyun
Yoon Soo-Jin
Lee Soo-Joo
|
|
|
Abstract
|
|
|
|
Autonomic dysfunction in patients with diabetic neuropathy causes significant impairment in functional status. Duloxetine, a serotonin-norepinephrine reuptake inhibitor, proved the efficacy in treating painful neuropathies including diabetic neuropathic pain. Although the use of duloxetine has been increasing recently, its potentially harmful effect on autonomic function was not properly assessed. We report a 52-year-old female diabetic patient who showed severe supine hypertension and extreme blood pressure variability following duloxetine administration. After stopping duloxetine, her vital signs have stabilized.
|
|
|
KEYWORD
|
|
|
Duloxetine hydrochloride, Hypertension, Diabetic neuropathies
|
|
|
FullTexts / Linksout information
|
|
|
|
|
|
Listed journal information
|
|
|
|